Applegate, J.A., et al., Systematic review of probiotics for the treatment of community-acquired acute diarrhea in children, BMC Public Health, 2013. 13 Suppl 3: p. S16.
Background: Oral rehydration salts (ORS), zinc, and continued feeding are the recommended treatments for community-acquired acute diarrhea among young children. However, probiotics are becoming increasingly popular treatments for diarrhea in some countries. We sought to estimate the effect of probiotics on diarrhea morbidity and mortality in children < 5 years of age.
While this review found some evidence that probiotics may be efficacious in reducing diarrhea duration and stool frequency during a diarrhea episode, data limitations resulting in this not been accepted as evidence for the use of probiotics as adjunct therapy in low- and middle-income countries.